---
title: Frequently Asked Questions about unsedated transnasal endoscopy or sedation-free TNE
description: EvoEndo’s FDA-Cleared product provides an alternative (for patients five and older) that may not require anesthesia/sedation
---

## Sedation-Free Transnasal Endoscopy (TNE) FAQs

#### [**** Is sedation-free TNE right for every patient? ](https://www.evoendo.com/physicianfaqs#)

According to studies, TNE was more acceptable and less stressful for patients overall compared with sedated transoral endoscopy.1-3

Every patient, whether their first procedure or their tenth, may have a different experience, so use your clinical judgment. Relative contraindications would be similar to other awake procedures.

#### [**** Is sedation-free TNE appropriate for patients with needle phobias? ](https://www.evoendo.com/physicianfaqs#)

Needles are not required for Sedation-Free TNE, which may make this procedure preferable to patients and families.

#### [**** Is the visual quality of the EvoEndo Scope similar to other scopes? ](https://www.evoendo.com/physicianfaqs#)

Yes, studies have shown that the EvoEndo® Model LE Gastroscope actually demonstrated improved optics over reusable ultra-slim scopes.1,5,6

#### [**** Is the quality of biopsies obtained via sedation-free TNE similar to those from larger reusable scopes? ](https://www.evoendo.com/physicianfaqs#)

Yes, multiple studies have confirmed that biopsy samples obtained via transnasal endoscopy are comparable to those obtained transorally with larger gastroscopes.1,5

#### [**** How do I learn how to perform sedation-free TNE with the EvoEndo Endoscopy System? ](https://www.evoendo.com/physicianfaqs#)

EvoEndo offers an extensive array of hands-on training options, support from clinical specialists, and a comprehensive library of literature, instructional videos, and other materials.

#### [**** How do I prep my patient for sedation-free TNE? ](https://www.evoendo.com/physicianfaqs#)

EvoEndo’s TNE patient video is a valuable resource for explaining TNE to patients and families. A pre-procedure introduction to a TNE program team member may also be helpful.

*References*

*1. Nguyen N, et al. Transnasal Endoscopy in Unsedated Children With Eosinophilic Esophagitis Using Virtual Reality Video Goggles. Clin Gastroenterol Hepatol. 2019 Nov;17(12):2455-2462.  
2.  Nguyen N, et al. Emerging Role of Transnasal Endoscopy in Children and Adults. Clin Gastroenterol Hepatol. 2022 Mar;20(3):501-504.  
3.  Cho S, et al. Unsedated transnasal endoscopy: a Canadian experience in daily practice. Can J Gastroenterol. 2008 Mar;22(3):243-6.  
4.  Scherer C, et al. Pediatric Patients’ and Parents’ Perspectives of Unsedated Transnasal Endoscopy in Eosinophilic Esophagitis: A Qualitative Descriptive Study. J Pediatr Gastroenterol Nutr. 2021 Apr 1;72(4):558-562.  
5.  Parker C., et al. Transnasal endoscopy: no gagging, no panic! Frontline Gastroenterol. 2016 Oct; 7(4): 246-256  
6. Nguyen N, et al. Transnasal Endoscopy in Unsedated Children With Eosinophilic Esophagitis Using Virtual Reality Video Goggles. Clin Gastroenterol Hepatol. 2019 Nov;17(12):2455-2462.*

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